BSL-3 Unit for In vivo And In vitro Models
Responsible person: Petr Bednář, M.Sc.
Our BSL-3 laboratories are designed for working with dangerous pathogens, not only those found locally, but also more exotic pathogens such as the Kyasanur Forest Disease virus and the Rift Valley Fever virus.
We offer a wide range of experimental options not only in in vitro models, but also in in vivo models of laboratory mice, complemented by an extensive virus collection. The most frequently used models in our laboratories include representatives of the flavivirus and coronavirus families, although we also work with other viral models.
Our services include not only individual comprehensive projects, but we can also process and analyze smaller sets of samples or even individual samples or experiments. In addition to experimental services, we also offer the opportunity to take a practical course in working in a BSL-3 laboratory. Please contact us for a more detailed assessment of your needs.
What services/products will the unit provide?
Biosafety and biosecurity consultations
- handling of risk group pathogens
- decontamination and disinfection procedures
- biocontainment
Experimental design for risk group 2 and 3 pathogens
- in vitro and in vivo
Training
- Biosafety course for BSL-2
- Biosafety course for BSL-3
In vitro models of viral infections
- available models for flaviviruses, coronaviruses, poxviruses, orthonairoviruses, and others
In vivo models of viral infections
- available models for flaviviruses, coronaviruses, and some others
Characterization of antivirals and antibodies
- in vitroand in vivo
- detection of antibodies against specific pathogens by VNT/ELISA
Decontamination and disinfection efficacy
- on surfaces and in liquids
- inactivation procedures for sample preparation
Processing and analyses of potentially risky samples
- samples from wild animals
- highly infectious samples from human patients
(please consult specific details in advance with Mr. Bednář; email: petr.bednar@sci.muni.cz)